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Featured Activity
Pros and Cons of Approved Therapies for Bipolar Depression and Ongoing Unmet Needs
Susan L. McElroy, MD

Learn about the effectiveness and adverse effects of approved bipolar depression treatments and discover areas for future study.

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Obsessive-Compulsive Disorder and Common Comorbidities
Charles F. Brady, PhD, ABPP

Find out about adjustments in both psychotherapy and pharmacotherapy for patients with OCD and comorbid depression, bipolar disorder, schizophrenia, or eating disorders.

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Monitoring Treatment and Managing Adherence in Schizophrenia
Stephen R. Marder, MD

Review ways to assess and address barriers to adherence and to monitor side effects that contribute to nonadherence and dangerous health conditions.

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Schizophrenia: Mechanism of Action of Current and Novel Treatments
Christoph U. Correll, MD, and John M. Kane, MD

New! Review the mechanism of action of available antipsychotics, learn why they're not effective for treating all symptoms, and find out about a potential treatment target.

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Depression: Managing the Full Range of Symptoms to Achieve Lasting Remission
John M. Zajecka, MD (Chair), et al

Do you treat your patients with MDD until they are asymptomatic? Read this CME Supplement to find out how to recognize, monitor, and treat residual symptoms.

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A Prospective 4-Year Naturalistic Follow-Up of Treatment and Outcome of 300 Bipolar I and II Patients
Christian Simhandl, Barbara König, and Benedikt L. Amann

Two-thirds of patients with bipolar disorder relapsed during a 4-year, naturalistic follow-up. Explore this and other findings in this CME article.

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Out of Sight, Out of Mind: The Case of a 62-Year-Old Man With Visual Complaints and Cognitive Decline
Saurav Das, Adam S. Fleisher, Roy Yaari, James D. Seward, Anna D. Burke, Helle Brand, and Pierre N. Tariot

Learn how vision problems and cognitive decline may be indicative of a variant of Alzheimer's disease.

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Working Together to Address Domestic Violence Among Veterans
Casey T. Taft, PhD

Get an overview of core themes in troubled relationships as well as ways to assess for, prevent, and address intimate partner violence in veterans and their families.

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Common Comorbidities and Differential Diagnosis of Restless Legs Syndrome
William G. Ondo, MD

Discover which disorders are often confused with restless legs syndrome (RLS) and which conditions and medications are associated with secondary RLS.

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multimedia curriculum
Monitoring Pharmacotherapy Response, Safety, and Tolerability to Enhance Adherence in Bipolar Disorder
Paul E. Keck, Jr., MD

New! Learn how to use rating scales to track efficacy and discover ways to monitor common side effects.

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Recognizing Primary Vs Secondary Negative Symptoms and Apathy Vs Expression Domains
Brian Kirkpatrick, MD, MSPH

Find out how to differentiate and treat the cause of negative symptoms and to recognize symptoms of apathy and diminished expression.

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Update on Treatment-Resistant Depression: Translating Clinical Science Into Effective Therapies
Michael E. Thase, MD

Review the burden of and risk factors for TRD, learn how to assess for treatment resistance, and find out about current and new therapeutic strategies.

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Measurement-Based Strategies to Assess and Manage Schizophrenia
Leslie Citrome, MD, MPH (Chair), et al

New! Discover how to distinguish between primary and secondary negative symptoms, find out how to assess treatment response, and review new therapeutic targets.

Strategies for Achieving Full Remission
Andrew A. Nierenberg, MD

Discover how to assess problems with first-line treatment and implement the best second-line treatment option to help your patients achieve asympomatic remission.

Please take our online poll

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Online Poll

Please answer the following questions about treating schizophrenia.

1. Mr A, your 35-year-old patient with schizophrenia, has achieved symptomatic remission, but you notice cognitive problems that might be hindering his progress in social and occupational areas. As you determine treatment goals in these areas, what interview-based assessment should you use to best measure Mr A’s cognitive abilities?

Quality of Life Scale (QLS)

UCSD Performance-Based Skills Assessment (UPSA)

Social Skills Performance Assessment (SSPA)

Schizophrenia Cognition Rating Scale (SCoRS)

2. Based on recent evidence, the most promising treatment target to address positive, negative, and cognitive symptoms of schizophrenia focuses on which of the following neurotransmitters?





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Science, Rhetoric, and the End of Psychosis
Andrew James Amos, MBBS

Dr Amos voices his concerns about bias in the early intervention in psychosis literature. He welcomes your comments.

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